Periodontal disease as a risk marker in coronary heart disease and chronic kidney disease periodontal disease the term periodontal diseases has been used for years to include all diseases of the soft and hard tissue surrounding the teeth ie the periodontium including gingivitis which is a reversible infection of the soft . Although dental caries tooth decay and periodontal gum disease are universally prevalent severe oral disease exists in only a minority of any population the three volumes comprising risk markers for oral diseases set out to characterize the at risk groups and define markers by which they can be identified. Biomarkers in periodontal disease 1 biomarkers in periodontal disease presented by shilpashivanand ii mds 2 contents introduction definition of biomarker candidates for biomarkers in periodontal disease sources of biomarkers microbiological markers immune and inflammatory markers cytosolic enzymes as markers enzymes released from host cells as markers connective tissue degradation products . The determination of biomarkers in saliva is becoming an important part of laboratory diagnostics and the prediction of not only periodontal but also other tissue and organ diseases biomarkers in saliva eg enzymes protein markers or oxidative stress markers can be used for activity determination and for periodontal disease prognosis. Periodontal diseases comprise a wide range of inflammatory conditions that affect the supporting structures of the teeth the gingiva bone and periodontal ligament which could lead to tooth
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